Non-SOT Publications of Interest
Criminal Poisoning: Clinical and Forensic Perspectives
By Authors Christopher P. Holstege, MD, Thomas Neer, and R. Brent Furbee, MD
A Comprehensive Study of Criminal Toxicology
Criminal Poisoning: Clinical and Forensic Perspectives offers health care providers, investigators and attorneys a comprehensive look at the history, employment and ex post facto analysis of criminal poisoning.
Drawing on the vast expertise of the authors—law enforcement agents and physicians with robust experience in the realm of criminal poisoning—Criminal Poisoning: Clinical and Forensic Perspectives covers the illegal use of poisons to harm people and the methods of detection available to investigators and prosecutors.
Each chapter covers a specific toxin, from acids and herbals to drugs of abuse, and includes a case study that explains the diagnostic challenges associated with detecting and prosecuting a criminal poisoning. What’s more, the book delves into who may poison—including the psychological factors that motivate someone to kill—and who may be a likely victim.
Criminal Poisoning: Clinical and Forensic Perspectives is a one-of-a-kind collaboration between medical practitioners and law enforcement agents, delivering the definitive resource for professionals on the topic.
Key features include:
- Information on unique toxins not discussed in other books, such as dioxin or trichothecene mycotoxin
- Both the clinical and forensic approaches to investigating criminal poisoning
- Illustrated text with in-depth descriptions of poisons including delivery, toxicology, detection and clinical effects
Guide for the Care and Use of Laboratory Animals
By the Committee for the Update of the Guide for the Care and Use of Laboratory Animals and the National Research Council
A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use:
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Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals.
- Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee.
- Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more.
- Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia.
- Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs.
The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.
Protecting the Immune System of Children
By Susan Lang
Exposure to pollutants, allergens, drugs and potentially harmful elements in the human diet abound and can damage the immune systems of embryos, babies and older children, says Cornell toxicologist Rodney R. Dietert, a professor of immunotoxicology in the College of Veterinary Medicine.
To help parents, physicians and other professionals prevent such damage in children, Dietert and his wife, Janice Dietert, have written the new book “Strategies for Protecting Your Child’s Immune System: Tools for Parents and Parents-to-Be” (World Scientific Publishing Co.).
Dietert
“It provides science-based information and specific strategies to help parents proactively protect their child’s immune system,” says Dietert.
The book covers environmental pollutants, over-the-counter and prescription drugs, vaccinations, infections, pets, hygiene, stress, maternal and childhood diets and safety testing of chemicals and drugs. It discusses such diseases and conditions as childhood asthma, allergies, diabetes, celiac disease, lupus, rheumatoid arthritis, autism, atherosclerosis, multiple sclerosis, leukemia and various diseases of later life. It also includes information about the immune system, various triggers of disease, prominent risks, developmental immunotoxicity testing and safety testing of chemicals and drugs for the developing immune system as well as strategies for preventing immune system damage, from prenatal environments to adulthood.
Intended for parents, family members, physicians, nutritionists, complementary health providers, teachers, college and medical students, and general readers, the book also covers how to plan reduced-risk, immunologically friendly environments, including home, school and playgrounds. Plus, it gives suggestions for correcting immune problems once they have occurred.
Book signing
Rodney Dietert will sign copies of his new book, “Strategies for Protecting Your Child’s Immune System: Tools for Parents and Parents-to-Be,” at the Cornell Store, June 12, 11:00 AM to 1:00 PM.
Earlier this year, “Immunotoxicity Testing: Methods and Protocols” (Springer/Humana), a technical book edited by Dietert, was published. The text provides current, lab-ready procedures, as well as corresponding background information that is necessary to identify effective testing approaches for chemicals and drugs.
ALTEX
By the Swiss Society ALTEX Edition
ALTEX, edited by the Swiss Society ALTEX Edition, is the official journal of CAAT (the Johns Hopkins Center for Alternatives to Animal Testing), EUSAAT (the European Society for Alternatives to Animal Testing), t4, the Transatlantic Think Tank of Toxicology (Baltimore, Utrecht, Konstanz), and the Doerenkamp chairs in Germany, India, The Netherlands, Switzerland, and USA. ALTEX is devoted to the publication of research on the development and promotion of alternatives to animal experiments according to the 3Rs concept of Russell and Burch: Replace, Reduce, and Refine. See http://altweb.jhsph.edu/altex.
ALTEX publishes original articles, short communications, and reviews, as well as news and comments, meeting reports, and book reviews. Animal experiments are defined by the editors as all experimental procedures involving the use of animals in testing, research, and education, or to obtain tissues, organs, and other animal derived products that may cause pain or distress to animals.
Training In Basic Biomethodology For Laboratory Rats
The National Human Genome Research Institute Office of Laboratory Animal Medicine, with support from the NIH Office of Animal Care and Use and the AALAS Foundation, has developed a training CD in “Basic Biomethodology for Laboratory Rats.” The CD compliments the training CDs in “Training in Survival Rodent Surgery” and “Training in Basic Biomethodology for Laboratory Mice.” It illustrates the most common practices used in the NIH intramural research program and was developed to promote proficiency in performing common techniques in the rat. It consists of nine training modules, table of contents, list of definitions and help and reference sections.
To obtain a copy of the CD send your name, research institution affiliation, full mailing address and e-mail address to rats_cd@mail.nih.gov. One CD per request please.
An Odyssey with Animals: A Veterinarian’s Reflections on the Animal Rights & Welfare Debate
By Adrian R. Morrison
Oxford University Press, New York, 2009.
288 pp. ISBN: 978-0-195-37444-5. $29.95.
The National Library of Medicine (NLM) Hazardous Substances Data Bank (HSDB)
The National Library of Medicine (NLM) Hazardous Substances Data Bank (HSDB) has added its first set of nanomaterial records. Nanotechnology is the study of matter on an atomic and molecular scale—structures 100 nanometers or smaller. A nanometer (nm) is one billionth of a meter.
Like other HSDB records, the nanomaterial records are peer-reviewed and contain information on toxicity, manufacturing and use, chemical and physical properties, environmental fate and exposure, and more.
There are currently seven HSDB nanomaterial records:
- Carbon nanotubes
- Fullerenes
- Silver nanoparticles
- Iron nanoparticles
- Titanium oxide nanoparticles
- Zinc oxide nanoparticles
- Cerium oxide nanoparticles
Information on hollow, spherical or ellipsoidal carbon nanostructures is found in the fullerenes record. The carbon nanotubes record contains information on tubular or lattice materials.
The fields of nanoparticles and nanostructures, as well as associated nomenclature, are continually evolving. Information and/or records will be added as data become available. The HSDB and nanomaterial records can be accessed on the TOXNET® Web site.
HSDB is a toxicology data file on the NLM Toxicology Data Network (TOXNET®). It focuses on the toxicology of potentially hazardous chemicals. It is enhanced with information on human exposure, industrial hygiene, emergency handling procedures, environmental fate, regulatory requirements, and related areas. All data are referenced and derived from a core set of books, government documents, technical reports and selected primary journal literature. HSDB is peer-reviewed by the Scientific Review Panel (SRP), a committee of experts in the major subject areas within the data bank's scope. HSDB is organized into individual chemical records, and contains over 5,000 such records.
Seahorse Bioscience Cellular Bioenergetics Webinar Series
Mitochondrial Bioenergetics in Disease: Toward a Mitochondrial Therapy of Muscular Dystrophies and Beyond Webinar.
Speaker—Paolo Bernardi, MD, Professor and Chair, Department of Biomedical Sciences, University of Padova
Mitochondrial Dysfunction and Apoptosis in Myopathic Mice with Collagen VI Deficiency 
William A. Irwin, Natascha Bergamin, Patrizia Sabatelli, Carlo Reggiani, Aram Megighian, Luciano Merlini, Paola Braghetta, Marta Columbaro, Dino Volpin, Giorgio M. Bressan, Paolo Bernardi, and Paolo Bonaldo
Nature Genetics, pp367–371, Vol.35, No. 4, December 2003
Natural Standard Herbal Pharmacotherapy—An Evidence Based Approach
by Catherine Ulbricht, PharmD
Natural Standard will provide preferred pricing to all Society of Toxicology Members.
- 30% discount for non-student members…$209 annual subscription rate.
- 33% discount for student members…$199 annual subscription rate.
To subscribe, contact Jonathan Lorino or at (617) 591-3334
648 pages | 2010
ISBN: 978-0-323-05184-2
Getting the Most out of Your Mentoring Relationships: A Handbook for Women in STEM
by Donna J. Dean
The Association of Women In Science (AWIS) is offering a new book on mentoring, Getting the Most out of Your Mentoring Relationships: A Handbook for Women in STEM, by Donna J. Dean.
One reviewer, Janet White of Kirin Pharma USA, said, “This is a survival handbook packed with juicy and practical advice…Unlike many books on mentoring, this guide is intended for the protégée, not the mentor.”
OLAW Publishes New Online Guidance Topic Index
The Office of Laboratory Animal Welfare (OLAW) has published a new online resource to OLAW Guidance categorized by subject matter. The new “Topic Index” allows one to browse and search OLAW responses to frequently asked questions, commentaries and articles written by OLAW staff, and policy notices published in the NIH Guide for Grants and Contracts.
The new Topic Index is found on the OLAW homepage under Guidance.
Animal Hematotoxicology: A Practical Guide for Toxicologists and Biomedical Researchers
By G. O. Evans, Wellcome Research Laboratories, UK (retired)
When looking for books in this field, you may find multidisciplinary books with chapters on toxicology, major textbooks written primarily for human medicine, or books geared toward the veterinary field, but few that focus on animal hematoxicology written specifically for laboratory scientists. Until now. Animal Hematotoxicology: A Practical Guide for Toxicologists and Biomedical Researchers explores the intersection of these fields and also those areas where the “rules” for human hematology and toxicology do not always apply.
Features:
- Presents information on main laboratory animal species with tables of reference values
- Includes a chapter on bone marow evaluation containing material on micronucleus tests in genetic toxicology
- Explores pre-analytical effects and the common laboratory measurements that indicate fundamental differences in cell counting techniques
- Discusses difference between blood cell numbers, shapes, and sizes for laboratory animals
- Provides key references on published reference ranges for laboratory animals
224 pages | 2008
ISBN: 978-1-4200-8009-4
USD: $79.95; £: $41.99
The Toxicology and Biochemisty of Insecticides
By Smon J. Yu, University of Florida, Gainesville USA
Considers the biological, physiological, and environmental consequences of pesticide use.
The first book in two decades to address this multi-faceted field, The Toxicology and Biochemistry of Insecticides provides the most up-to-date information on insecticide classification, formulation, mode of action, resistance, metabolism, environmental fate, and regulatory legislation. The book draws on the author's groundbreaking research in insect detoxification. It discusses mechanisms at the molecular level such as specific enzymes that contribute to insecticide susceptibility and influence hose plant selections in phytophagous insects.
Beginning with a general introduction, eleven chapters integrate classical toxicology with physiology, biochemisty, and molecular biology to present a comprehensive look at the field. The book discusses the demand and formulation of pesticides and describes each type from dusts and powders to baits and aerosols. It classifies insecticidesby target, chemical compound, and mechanism; evaluates toxicity testing procedures; explains pesticide uptake, mode of action, and metabolism; and explores species differences, resistance, and interactions. It also considers pesticides in the environment and federal and state regulatory legislation and enforcement.
A long-waited, state-of-the-science review on insect toxicology, this indispensable book brings you up-to-date on the many aspects and implications of pesticide use and provides the necessary background and platfom from which to conduct future research.
296 pages | 2008
ISBN: 978-1-4200-5975-5
USD: $99.95; £: $39.99
Principles of Food Toxicology
By Tõnu Püssa, Estonian University of Life Sciences, Tartu Estonia
Skillfully combining theory and applications, this text introduces toxicology principles at the molecular, cellular, and organism level. The author uses vivid examples, as well as highly detailed, yet accessible information, to emphasize the biochemical mechanisms of toxic effects and toxic response. The book also provides a systemic characterization of the most important food borne toxicants.
- Combines general principles of toxicology with the characterization of food-borne toxicants
- Explains the biochemistry and chemistry required for thorough understanding of toxicological principles
- Provides explanations of the mechanisms of toxic effect and medicinal consequences
- Features a comprehensive catalog of all of the most important food-borne toxicants
344 pages | Hardcover | 2008
ISBN: 978-0-8493-8090-7
USD: $69.95; £: $33.99
Environmental Toxicants: Human Exposures and Their Health Effects
By Morton Lippmann, New York University Medical Center, USA
Gain the most current information and research available for performing risk assessments on exposed individuals and populations. Giving guidance to public health authorities, primary care physicians, and industrial managers, this third edition:
- Reviews current knowledge on human exposure to selected chemical agents and physical factors in the ambient environment
- Updates and revises the previous editio, in light of current scientific literature and its significance to public health concerns
- Includes new chapters on: airline cabin exposures, arsenic, endocrine disruptors, and nanoparticles.
1008 pages | Hardcover | 2009
ISBN: 978-0-471-79335-9
USD: $175.00; CAD: $178.99
Molecular and Biochemical Toxicology (Fourth Edition)
By Robert C. Smart; Ernest Hodgson, North Carolina State University, USA; Editors
Clear and comprehensive, this book covers a range of dynamic aspects in biochemical and molecular toxicology. Compiled and authored by a diverse group of experts, it guides students and professional toxicologists through a broad rand of issues and helps solve problems of basic toxcology questions, integrating myriad fields from nutrition to genetics to toxicology. This latest edition adds timely and thorough coverage of molecular toxicology, including proteomics, toxicogenomics, metaolomics, pharmaco (toxico) genetics.
944 pages | Hardcover | 2008
ISBN: 978-0-470-10211-4
USD: $125.00; CAD: $137.99
On-line Book: ISBN: 978-0-470-28525-1
Fundamentals of Analytical Toxicology
By Robert J. Flanagan, King's College Hospital NHS Foundation Trust, UK; Andrew A. Taylor, Royal Surrey County Hospital, UK; Ian D. Watson, Aintree Hospitals, UK; Robin Whelpton, Queen Mary, University of London, UK
This book aims to give principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. The book covers aspecs of sample collection, transport, storage and disposal, and sample preparation as well as general aspects of method implementation/validation and laboratory operation. It concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results.
544 pages | Hardcover or Paperback | 2008
ISBN: 978-0-470-31934-5 or 31935-2
USD: $180.00 or $80.00; CAD: $197.99 or $87.99
On-line Book: ISBN: 978-0-470-51629-4
Toxicology and Risk Assessment: A Comprehensive Introduction
By Helmut Greim, Technical University of Munich; Robert Snyder, The State University of New Jersey, USA; Editors
Describing the basic concepts of toxicology, Toxicology and Risk Assessment equips you with the skills required to evaluate risks at given exposures. Topics covered include:
- Principles in Toxicology: toxicokinetics including absorption, distribution, metabolism, and excertion; the mechanisms that lead to cytotoxicity, carcinogenicity and effects on reproduction, and the toxic effects on mixtures of chemicals
- Organ Toxicology: information on anatomy and physiology of the major organs; why they are specific targets; and the mechanisms of specific chemicals affecting these organs
- Methods in Toxicology: the commonly used methods used for toxicity testing, both in vivo and in vitro.
698 pages | Hardcover | 2008
ISBN: 978-0-470-86893-5
USD: $150.00; CAD: $164.99
On-line Book: ISBN: 978-0-470-86895-9
Hepatotoxicity: From Genomics to In Vitro and In Vivo Models
By Saura Sahu, Editor
Hepatotoxicity is an authoritative compilation of the most recent advances in this important discipline, presented by international experts and demonstrating the multidisciplinary nature of this science. With this work, you'll gain essential insight into current trends in this area of research and the future directions it may take. A partial sampling of topics covered includes biomarkers of hepatotoxicity, genomics of hepatotoxicity, gender difference in hepatotoxicity, hepatotoxicity of botanical supplements, and risk assessments of hepatotoxins.
704 pages | Hardcover | 2008
ISBN: 978-0-470-05716-2
USD: $250.00; CAD: $274.99
On-line Book: ISBN: 978-0-470-51675-1
The Dose Makes the Poison: A Plain-Language Guide to Toxicology
By M. Alice Ottoboni
Improve your understanding to toxic chemicals without taking the time to go back to school. Thoughtful discussions of controversial issues help you to understand news media reports on toxicology, avoid the half-truths that lead to “poison paranoia,” and make informed judgments about our use and control of chemicals. The Dose Makes the Poison, Second Edition, is an easy-to-read review of toxicology that has become “required reading” for scientists and managers throughout industry, public health officials, environmental scientists, industrial hygienists, and hazardous waste workers.
256 pages | Paperback | 1996
ISBN: 978-0-471-28837-4
USD: $59.95 CAD: $65.99
Patty's Industrial Hygiene and Toxicology
By Eula Bingham, Barbara Cohrssen, Charles H. Powell
Hailed by industry experts as the most reliable, comprehensive, and state-of-the-art reference on the principles and practice of industrial hygiene and occupational health and safety, Patty's Industrial Hygiene and Toxicology is now more accessible that ever before. Containing all 13 volumes of the print edition, this CD-ROM offers quick access to current information on industrial hygiene, occupational safety, toxicological properties of chemical agents, research trends, regulations, permissible exposure level data, and much more. Patty's CD-ROM includes full texts, charts, tables, and illustrations from the celebrated reference, and features:
- Simple and complex Boolean searching capabilities
- Hyperlinked references, tables, and figures
- Comprehensive electronic index for the entire database.
CD-ROM | 2005
ISBN: 978-0-471-70057-9
USD: $1113.50; CAD: $1224.99
Toxicogenomics: A Powerful Tool for Toxicity Assessment
By Saura Sahu, US Food and Drug Administration
Toxicogenomics delivers up-to-date state-of-the-art information presented by recognized experts, and so serves as an authoritative source of curent knowledge in this field of research. The potential link between toxicology, genetics, and human diseases makes this book very useful to investigators in many and varied disciplines of science and toxicology. A sampling of the many topics covered include mechanistic toxicogenomics, the analysis and interpretation of toxicogenomics as a tool to assess immunotoxicity, and the application of toxicogenomics in drug discovery.
416 pages | Hardcover | 2008
ISBN: 978-0-470-51823-6
USD: $190.00; CAD: $208.99
On-line Book: ISBN: 978-0-470-69963-8
Nanoscience and Nanotechnology: Environmental and Healh Impacts
By Vicki H. Grassian, Editor
Covering various aspects of nanoscience and nanotechnology and what is know about the potential environmental and health impacts, this comprehensive book addresses the toxicity of nanomaterials, fate and transport of nanomaterials in the environment, and occupational health aspects of nanotechnology.
- Brings together, uniquely in on source, research on environmental implications of nanotechnology and engineered nanoparticles
- Has broad interdisciplinary appeal for chemist, engineers, environmental scientists, material scientists, toxicologists, occupational and environmental health specialists, and regulatory personnel
496 pages | Hardcover | 2008
ISBN: 978-0-470-08103-7
USD: $99.95; CAD: $109.99
On-line Book: ISBN: 978-0-470-39661-2
Handbook of Toxicogenomics: A Strategic View of Current Research and Applications
By Jürgen Borlak, Fraunhofer Institute of Toxicology and Experimental Medicine, Germany; Editor
Toxicogenomics is a new, dynamic and very promising field that can help optimize toxicity analyses and streamline research into active substances. It is of interest not only for basic research and development, but also from a legal and ethical perspective. Here, expets from all the fields mentioned will find solid information provided by an international team of experienced authors. With its approach as an interdisciplinary overview, it will prove particularly useful for all those needing to develop appropriate research strategies.
705 pages | Hardcover | 2005
ISBN: 978-3-527-30342-7
USD: $305.00; CAD: $335.99
On-line Book: ISBN: 978-3-527-60371-8
Computational Toxicology: Risk Assessment for Pharmaceutical and Environmental Chemicals
By Sean Ekins, Editor
This unique volume explains how the interaction of molecules with toxicologically relevant targets can be predicted using computer-based tools. You'll discover how QSAR methods are applied to enzymes, transporters, nuclear receptors, and ion channels. The book also clearly shows how in vitro models are used, covers newer technologies, and addresses regulatory aspects. It offices a complete systems perspective regarding risk assessment prediction and discusses experimental and computational approaches in detail. There are also sections on applying computers to toxicology assessment in the pharmaceutical industry and in the environmental arena.
814 pages | Hardcover | 2007
ISBN: 978-0-470-04962-4
USD: $145.00; CAD: $159.99
On-line Book: ISBN: 978-0-470-14589-0
Toxicogenomics: Principles and Applications
By Hisham K. Hamadeh, Cynthia A. Afshari, both of Amen, Inc. USA; Editors
Providing a unified, thorough text on key breakthrough technololgies in genomincs, proteomics, metabonomics, and bioinformatics, as well as their applications to toxicology research, this book includes:
- A general introduction to toxicology for nonspecialists
- Microarray/high-density gene expression profiling
- Quantitative RNA measurement
- Analysis of metabolites (metabonomics)
- Statistics and databases for toxicogenomics
- Functional genomics models
- Protein analysis and profiling.
361 pages | Harcover | 2004
ISBN: 978-0471-43417-7
USD: $90.50; CAD: $99.99
On-line Book: ISBN: 978-0-471-66904-3
The ILSI Health and Environmental Sciences Institute (HESI)
The ILSI Health and Environmental Sciences Institute (HESI) requests proposals on emerging issues for 2009. Deadline for submission: Tuesday, September 2, 2008. Please visit the Web site for more information.
Just published!
Toxicology Principles for the Industrial Hygienist
Edited by William E. Luttrell, Warren W. Jederberg, and Kenneth R. Still
AIHA's Toxicology Principles for he Industrial Hygienist, the most comprehensive toxicology reference, is written by industry experts specifically for the industrial hygienist. Emphasis is on basic principles and case studies that relate to the working environment. This book is recommended for classroom text as well as a professional resource.
The book's 36 chapters provide thorough discussions of
- Understanding Toxicology
- Sites of Action of Chemicals Found in the Workplace
- Chemical Group Toxicology
- Application of Toxicological Information
- Sources of Toxicological Information
453 pages | Softcover | 2008
Stock number: BTOR08-738
AIHA Member Price: $98; Non-member Price: $123
To order visit www.aiha.org/market or call AIHA Customer Service at (703) 849-8888, Monday–Friday, 9:00 AM–5:00 PM ET.
NLM's Disaster Information Management Research Center (DIMRC)
The National Library of Medicine has released a web resource for the
Disaster Information Management Research Center (DIMRC) http://disasterinfo.nlm.nih.gov. The DIMRC web site seeks to provide access to quality disaster health
information at all stages of preparedness, response, mitigation, and
recovery. DIMRC will focus its efforts on providing disaster health
information resources and informatics research that will be directly
beneficial for public health officials, healthcare providers, special
populations, and the public.
Carcinogenic Potency Database
CPDB, the Carcinogenic Potency Database, was developed by the
Carcinogenic Potency Project at the University of California, Berkeley,
and by the Lawrence Berkeley National Laboratory. CPDB includes 6540 chronic, long-term animal cancer tests (both positive
and negative for carcinogenicity) from the general published literature
as well as from the National Cancer Institute and the National
Toxicology Program. Such tests are used in support of cancer risk
assessments for humans. Information that is important in the
interpretation of bioassays is reported in CPDB for each experiment.
Users can search for results on each chemical in TOXNET via chemical
name or name fragment, or by Chemical Abstracts Service Registry Number
(RN). Results include a summary for each sex-species tested, including
carcinogenicity, target organs, and carcinogenic potency values.
Detailed results from each experiment on the particular chemical are
given in a plot format suitable for screen viewing. Chemical structure,
InChI, and SMILES codes are reported.
National Library of Medicine Resource Update: Dietary Supplements
The National Library of Medicine's Dietary Supplements Labels Database http://dietarysupplements.nlm.nih.gov includes information from the
labels of over 2,000 brands of dietary supplements in the marketplace,
including vitamins, minerals, herbs or other botanicals, amino acids,
and other specialty supplements. The database is designed to help both the general public and health care
providers find information about ingredients in brand-name products,
including name, form, active and inactive ingredients, amount of active
ingredient/unit, manufacturer/distributor information, suggested dose,
label claims, warnings, percentage of daily value, and further label
information.
Sittig’s Handbook of Toxic and Hazardous Chemicals and Carcinogens, 5th Edition
Provides information on chemical hazards that could impact our way of life. The book address safety data for chemicals in cleaning solvents, pharmaceuticals, plastics…etc.
The Second Edition of the International Union of Pure and Applied
Chemistry (IUPAC) “Glossary of Terms Used in Toxicology” has been added
to the National Library of Medicine (NLM)'s Division of Specialized
Information Services (SIS) Web site at: http://sis.nlm.nih.gov/enviro/iupacglossary/frontmatter.html
The Second Edition glossary contains definitions and explanatory notes
for terms frequently used in the multidisciplinary field of toxicology.
It also contains a list of abbreviations and acronyms used in
toxicology, a list of abbreviations and acronyms used by international
bodies and by legislation relevant to toxicology and chemical safety,
and a listing of the classifications of carcinogenicity according to the
weight of evidence available.
Now Available: Enhanced ToxSeek Meta-Search Engine and
Clustering Tool
An updated version of ToxSeek is now available
(toxseek.nlm.nih.gov). ToxSeek is an NLM metasearch engine and
clustering tool that enables the simultaneous searching of many
different toxicology and environmental health information databases and
web sites.
ToxSeek enhancements include:
- A new spell checker with English and medical dictionaries
- The automatic
inclusion of medical subject headings (MeSH) in the subject clusters
- The addition of TOXMAP (environmental health e-maps) and ToxTown
(an interactive guide to commonly encountered toxic substances)
- Refinements to the search strategies of the CPSC (Consumer Product
Safety Commission) and CDC (Centers for Disease Control and Prevention)
sites
- The addition of WHO (World Health Organization).
Toxipedia is a free toxicology encyclopedia and resource center providing comprehensive,
accurate, and scientifically based information on the hazards and risks
of chemical and physical agents, with the goal of advancing human and
environmental health. The site includes a quality control system too.
A New Frequently Asked Question (FAQ) is now posted on the OLAW website
at: www.grants.nih.gov/grants/olaw/faqs.htm
This FAQ provides guidance on the roles of the Institutional Official
and the IACUC in developing plans to diminish the likelihood that their
institution or its employees will become targets of animal activists.
Institutions are encouraged to review OLAW FAQs and make use of this
resource.
Free Access to the New Online Archive of the Royal Society
Access, the most complete
350-year-old archive of journals for the Royal Society, includes every paper
published in the Royal Society journals since 1665. The vice president
and chair of the Publishing Board, Professor Martin Taylor, described
the uniqueness of the collection as holding interest not only for
scientists but also for anyone with an interest in history. "The rich,
varied, and sometimes entertaining archive documents the earliest
accounts of the seventeenth century's new experimental philosophy,
through which an understanding of the natural world was acquired by
experiment and observation. www.pubs.royalsoc.ac.uk.
New Brochure on PHS Policies on Humane care and Use of Laboratory Animals
OLAW has created a brochure intended to communicate to investigators
their responsibilities under PHS Grants Policy and PHS Policy on Humane
Care and Use of Laboratory Animals. What Investigators Need to Know About
the Use of Animals provides a succinct resource for investigators to
quickly grasp the main expectations and requirements when using animals
in research supported by the PHS. The brochure may be accessed at http://grants.nih.gov/grants/olaw/InvestigatorsNeed2Know.pdf.
OLAW will provide institutions with enough copies to disseminate to all
of their investigators that work with animals. Send requests, along with
the number of copies needed, to olaw@od.nih.gov, and please be sure to
provide your complete mailing address.
CiteULike—Free Service for Academics to Share, Store and
Organize papers
CiteULike is
a free service to help academics to share, store, and organise the academic
papers they are reading. When you see a paper on the web that interests
you, you can click one button and have it added to your personal library.
CiteULike automatically extracts the citation details, so there's no need
to type them in yourself. It all works from within your web browser. There's
no need to install any special software. Because your library is stored
on the server, you can access it from any computer. You can share your
library with others, and find out who is reading the same papers as you.
In turn, this can help you discover literature which is relevant to your
field but you may not have known about.
ScienceSlides—The Leading Tool for Scientific Lectures
and Seminars
ScienceSlides is a lecture and seminar companion for Microsoft
Powerpoint aimed at helping scientists and teachers to create professionally
looking slides quickly. Available for both Mac OSX and Microsoft Windows,
for more information and a demonstration about ScienceSlides 2006 visit
www.visiscience.com.
Improved and Updated 2006 Version now available! Over 400 new compounds
and slides. Numerous updates in all fields, expanded diabetes, obesity
and cardiovascular sections. New feature—References in selected
Molecular Pathology and Signaling slides.
Who is ScienceSlides
made
for? Scienceslides for PowerPoint is an indispensable tool for time—conscious
scientists and educators in biomedical fields who require professional presentation
material to support their scientific presentations.
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Training
CD in basic Methodology for Laboratory Mice available from NIH
The National Human Genome Research Institute Office of Laboratory
Animal Medicine has developed a training CD in Basic Methodology
for Laboratory Mice that illustrates the most common practices used
in the NIH intramural research program. It was developed to promote
proficiency in performing common techniques in the mouse. It consists
of eight training modules, table of contents, list of definitions,
and help and reference sections. To obtain a copy of the CD, send
your name, research institution affiliation, full mailing address
and email address to rodent-cd@mail.nih.gov
. One CD per request, please. From AMP News Service Digest, Monday,
January 17, 2005.
Dermatotoxicology,
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It is unparalleled in its coverage, and this new edition broadens
its scope to include chapters on:
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Quantitative Structure Activity Relationships (QSARs)
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the past 25 years. The book concludes with a “future challenges”
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Current Protocols in Toxicology, Contact: John
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Journal of Toxicology and Environmental Health, Part B: Critical Reviews. In keeping with the original scope of Part A, Part B focuses on environmental toxicology in general as well as on special interest fields such as: environmental factors affecting health; target organ toxicities; immunotoxicology; risk assessment; carcinogenesis and mutagenesis; ecotoxicology and aquatic toxicology.
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Risks Associated with Smoking Cigarettes with Low Machine-Measured Yields of Tar and Nicotine, The National Cancer Institute (NCI) Tuesday released this 251-page monograph detailing the dangers of “low tar” cigarettes. The monograph, the thirteenth in NCI's Smoking and Tobacco Control Monograph Series, reports findings that reductions in cancer rates are due to decreases in smoking prevalence not to changes in cigarette design, which according to NCI, have done little to address public health needs in the past 50 years. NCI here reports on ways in which smokers compensate for lower levels of tar and nicotine, reasons why Federal Trade Commission (FTC) testing methods are inadequate, and marketing methods designed to give smokers a false sense of security regarding low tar and nicotine cigarettes. Users can download the monograph by chapter or as a whole in pdf format.
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